Formulation Development of Flaxseed Oil Beads Containing ω-Fatty Acid

نویسندگان

چکیده

Background: Nutraceuticals are in high demand as dietary supplements on the international market since decades. Nutritional and therapeutic called nutraceuticals widely accessible. Alpha linolenic acid (ALA), fibre, proteins, vital omega-3 fatty acids all present concentrations flaxseed, one of oldest most utilised food supplements. The work was aimed to formulate develop flaxseed oil beads containing omega a replacement supplement for marine source. Flaxseed were formulated by ionic gelation method. Minitab 21.1.0 used screen optimise process formulation parameters. Plackett Burman design initial screening. Twelve batches made ready screening, each batch evaluated optimization based percentage drug release encapsulation efficiency. RSM carry out optimization. After validation, showed satisfactory results complying with IP specifications.
 Results: efficiency release. F4, F6 F10 shown optimal results.
 Conclusion: Polyunsaturated found confirmed hexabromide test. Several nutritional advantages extracted oil's incorporated utilising process.
 Keywords: Nutraceutical, Flaxseed, Beads, QbD, Omega acid, acid.

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ژورنال

عنوان ژورنال: Journal of Drug Delivery and Therapeutics

سال: 2022

ISSN: ['2250-1177']

DOI: https://doi.org/10.22270/jddt.v12i6-s.5877